Cardiac Tumor with Dual Component of Myxoma and Angiofibroma Presented with Syncope: An Extremely Rare Case Report

Akhlaghpasand, Mohammadhosein; Rahab, Mehdi; Farahani, Setayesh; Hosseinpour, Melika; Zeraatian Nejad Davani, Sam

Cardiac Tumor with Dual Component of Myxoma and Angiofibroma Presented with Syncope: An Extremely Rare Case Report

Document Type : Case Report

Authors

Mohammadhosein Akhlaghpasand ¹^{, 2}

Mehdi Rahab ³

Setayesh Farahani ¹^{, 2}

Melika Hosseinpour ¹^{, 2}

Sam Zeraatian Nejad Davani ⁴^{, 3}

¹ Cardiothoracic Surgery Research and Development Committee, Iran University of Medical Sciences (IUMS), Tehran, Iran2. Rockingham Medical Research Centre, Rockingham, Australia.

² Rockingham Medical Research Centre, Rockingham, Australia

³ Department of Cardiovascular Surgery, Rasool Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran

⁴ Rockingham Medical Research Centre, Rockingham, Australia,

Abstract

Background: Primary cardiac tumors (PCT), such as myxoma, are rare and predominantly benign. Angiofibroma tumors are an extremely rare subtype of PCT, reported in less than ten cases. In this study, we presented a mixed tumor of myxoma and angiofibroma for the first time in the human heart.
Case Presentation: This case report describes a 30-year-old man with a positive cerebrovascular accident (CVA) history who presented with syncope, aphasia, and right-side hemiparesis to the emergency department. The imaging assessment, including echocardiography and magnetic resonance imaging, revealed a suspected cardiac tumor in his left atrium extended to the interatrial septum. Therefore, during tumor resection surgery, the mass was removed entirely. Microscopical pathology and desmin immunohistochemical and trichrome staining findings confirmed the angiofibroma diagnosis with myxoma components.
Conclusion: According to our presentation, angiofibroma can be accompanied by myxoma and result in neurological symptoms. The best treatment for this dual-component tumor is surgical resection of the tumor and the affected margin.

Keywords

Cardiac Tumor

Myxoma

Angiofibroma

Syncope

Subjects