Successful Treatment of Massive Pulmonary Thromboembolism with Reteplase: Case Series

Document Type : Original Article


Department of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran


Massive pulmonary thromboembolism (PTE) has an increased risk of mortality. Thrombolytic therapy is the accepted treatment. Reteplase, a variant of tissue plasminogen activator, has been used in acute myocardial infarction with acceptable safety and efficacy, but studies in massive PTE are rare. In this study we report five cases of successful treatment of massive PTE with reteplase.