Tumor-to-Tumor Metastases from Lung Carcinoma to Soft Tissue Fibrous Histiocytoma


1 Department of Respiratory Medicine,

2 Department of Pathology, Urmia University of Medical Sciences and Health Services, URMIAIRAN.


Tumor-to-tumor metastases are uncommon. Lung cancer is the most frequent donor tumor while renal cell carcinoma is the most common malignant, and meningioma the most common benign recipient of metastases. Other reported host benign lesions include thyroid adenoma, adrenocortical adenoma, ovarian cystoma, and hepatic cavernous angioma. A 41-year-old male smoker presented with a mass in the right axillary’s fossa, cough and weight loss. Chest x-ray showed left lung collapse. Fiberoptic bronchoscopy showed vegetation in the left main bronchus and biopsy revealed adenocarcinoma. Biopsy of the right axillary mass showed benign fibrous histiocytoma (BFH) with metastasis from adenocarcinoma. To our knowledge, this report represents the first case of tumor-to-tumor metastasis to BFH. (Tanaffos 2008; 7(3): 73-75)