Pulmonary Alveolar Microlithiasis and Osteopetrosis


1 Department of Otolaryngology, Shahed University,

2 Department of Pathology, Kermanshah University of Medical Sciences,

3 Department of Infectious Disease, Shahed University, TEHRAN-IRAN.


Pulmonary alveolar microlithiasis is a rare condition caused by deposition in the alveoli of the lungs by calcific consolidation called calcospherites. Its etiology and pathogenesis are obscure. Osteopetrosis is a heterogeneous group of inheritable conditions with a defect in bone resorption by osteoclasts. We report a case of pulmonary alveolar microlithiasis associated with osteopetrosis, which was diagnosed incidentally by bone high density and generalized osteosclerosis on chest x-ray. Association of these two diseases has not been reported before. (Tanaffos 2008; 7(4): 60-63)