Electrocardiographic and Echocardiographic Findings in Patients with Pulmonary Sarcoidosis


1 Cardiology Unit,

2 Department of Pulmonary Medicine, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN


Background: Sarcoidosis is a multisystemic granulomatous disease, in which cardiac involvement is one of the most important causes of death. Conduction abnormalities are the most common cardiac finding. Materials and Methods: Electrocardiographic and echocardiographic changes of 40 patients with pulmonary sarcoidosis who referred to a cardiac unit were evaluated. For all cases, a complete history, 12-lead ECG, and a transthoracic echocardiogram were achieved. None of them had history of underlying heart disease. Data analysis was performed using descriptive statistical parameters. Results: The study population included 24 females and 11 males with the mean (±SD) age of 47.8±8.6 years. Echocardiographic indices including systolic function and total cardiac function indices as well as the size of cavities and valves status were in normal limit in most patients. Only in 5% of patients, ejection fraction (EF) was slightly diminished. In 42.5% of cases, diastolic dysfunction was detected. Electrocardiographic evaluation showed first degree AV block only in one case and T inversion in leads V1-V6 in another subject. Conclusion: Our study showed that cardiac involvement presenting as electrocardiopraphic abnormality was seen in 2 cases. Diastolic involvement was a remarkable finding in our study. This as well as a slight decrease of 5% in EF requires further investigation. A study with a greater sample size, better follow up, and using other diagnostic means, can be helpful. (Tanaffos 2002; 1(4): 69-72)