Respiratory Disturbance Index and Severity of Airway Obstruction in COPD Patients


1 Department of Pulmonary Medicine

2 Tobacco Prevention and Control Research Center

3 Department of Pulmonary Medicine,

4 Lung Transplantation Research Center, NRITLD, Shahid Beheshti University M.C., TEHRAN-IRAN


Background: Chronic obstructive pulmonary disease (COPD) is a common disease and concomitant occurrence with obstructive sleep apnea (OSA) has been reported in some studies. This coincidence can result in exacerbation of common complications like exacerbated hypoxemia, hyperpnea and right-sided heart failure. Thus, we decided to evaluate and compare respiratory disturbance index (RDI) and sleep apnea in COPD patients. Materials and Methods: For this purpose, 50 COPD patients with OSA were studied between 2003 and 2004. OSA criteria included obstructive apnea and clinical symptoms of snoring, sleep disorder and RDI≥5. The patients were divided in to two groups: group 1 consisted of 11 patients (22%) with FEV1/FVC