Serum Troponin Levels, APACHE II Score and Mortality Rate for Non-Cardiac Reasons in RCU Patients


Department of Pulmonary Medicine, Labbafi-Nejad Hospital, Shahid Beheshti University M.C., TEHRAN-IRAN.


Background: Estimating the severity of disease and prognosis for patients hospitalized in intensive care units may be important in selection of diagnostic procedures and treatment regimens. For this purpose, various ranking methods have been used in these units which have their benefits and shortcomings. Materials and Methods: In this study, all patients admitted to the respiratory intensive care unit (RCU) of Labbafi Nejad Hospital during the year 2005 with no signs of cardiac disease or history of cardiopulmonary resuscitation were evaluated. All patients had their serum troponin level checked in the first hour of hospitalization in the unit and upon first medical examination acute physiologic and chronic health evaluation (APACHE) II scores were determined for them. In total, 87 patients were eligible for entering the study. Results: There were significant correlations between serum troponin levels and APACHE II score (p=0.0001). There was also a significant correlation between elevated troponin levels and mortality rate. Multivariate statistical analysis showed that APACHE II scores and serum troponin levels each are independent variables affecting prognosis among hospitalized patients in the respiratory intensive care unit. Conclusion: Determination of serum troponin levels in non-cardiac patients admitted to respiratory intensive care unit can be a helpful prognostic factor. (Tanaffos 2009; 8(1): 29-34)