Rapid Recovery of Diabetes Two Months after Discontinuation of Tacrolimus (FK-506) in a Single Lung Transplant Patient


1 Department of Pulmonary Medicine

2 Lung Transplantation Research Center, NRITLD, Shahid Beheshti University M.C., TEHRANIRAN.

3 Department of Pulmonary Medicine,


Post-transplant diabetes mellitus (PTDM), developing in almost one quarter of renal transplant patients within three years after the procedure, contributes to post-transplant morbidity and mortality by increasing the risk of infection and cardiovascular events. PTDM is considered a variant of diabetes mellitus (DM) type II and results in similar microvascular and macrovascular diabetic complications seen in non-transplant patients. In this article, we present a case of single lung transplant patient who developed PTDM with a severe DKA as the first manifestation of the disease. PTDM resolved rapidly after discontinuing tacrolimus. (Tanaffos 2009; 8(4): 55-59)