Castleman's Disease in a 35 Year-Old Woman with a Giant Mediastinal Mass


1 Department of Thoracic Surgery

2 Department of Pulmonary Medicine, Respiratory Disease and TB Research Center, Guilan University of Medical Sciences(GUMS) - Razi Hospital- RASHT- IRAN.

3 Department of Thoracic Surgery,


The patient was a 35 year-old woman with a 10-month history of breathing difficulty, cough and chest pain. An anteriorposterior chest radiograph revealed opacification of the right hemithorax with reduced right lung volumes. As part of diagnostic evaluation, a computed tomography (CT) scan was performed which showed a huge mass in the right anterior mediastinum with extension to the right side of the pleural space. It was resected through postero-lateral thoracotomy .The patient was discharged in a good condition. The pathology report showed hyaline vascular variant of Castleman,s disease. (Tanaffos 2009; 8(4): 51-54)