Forced Expiratory Flow at 25–75% as a Marker for Airway Hyper Responsiveness in Adult Patients with Asthma-like Symptoms

Raji, Hanieh; Haddadzadeh Shoushtari, Maryam; Idani, Esmaeil; Tavakol, Heshmatollah; Afrakhteh, Sakineh; Dastoorpoor, Maryam; Borsi, Seyed Hamid

Forced Expiratory Flow at 25–75% as a Marker for Airway Hyper Responsiveness in Adult Patients with Asthma-like Symptoms

Authors

Hanieh Raji ¹

Maryam Haddadzadeh Shoushtari ¹

Esmaeil Idani ¹

Heshmatollah Tavakol ¹

Sakineh Afrakhteh ²

Maryam Dastoorpoor ²^{, 3}

Seyed Hamid Borsi ¹

¹ Air pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

² Air pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran,

³ Department of Epidemiology and Biostatistics, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract

Background: The aim of the present study was threefold: to assess the association between baseline FEF25-75 and Airway Hyper-responsiveness (AHR), to specify whether a decrease in FEF25-75 may reflect severe hyperresponsiveness, and finally to confirm a FEF 25-75 cut-off value. Materials and Methods: In a cross sectional study in Imam Khomeini Hospital, Ahvaz, patients suffering from respiratory symptoms due the 2013 autumn rainfall with normal FEV1 and FEV1/FVC were evaluated by methacholine challenge test. Those with PD20

Keywords

Airway Hyper-Responsiveness

Methacholine Challenge Test

Asthma

FEF25-75