1
1Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
2
Chronic Respiratory Disease Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3
1Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
Pneumocystis pneumonia (PCP) is a common opportunistic infection in immunocompromised patients. In general, clinical response to therapy with cotrimoxazole is excellent. However, therapy may be limited by side effects or treatment failure. We present a case of PCP in a 35-year-old male patient with history of heart transplantation and renal failure who was admitted with a 10- day history of fever, nonproductive cough and elevated level of creatinine with a diagnosis of PCP confirmed by chest radiography and in bronchoalveolar lavage specimens. He was treated with trimethoprim-sulphamethoxazole (SMZ/TMP) and primaquine but treatment was completed with reduced dosage of cotrimoxazole, primaquine and with the addition of caspofungin. This therapy was effective and without any adverse effects in a patient with elevated level of creatinine
Abolghasemi, S., Sharif-Kashani, B., Naghashzadeh, F., Marjani, M., Monir, A., Doroudinia, A. & Tabarsi, P. (2018). Caspofungin as Salvage Therapy for Pneumocystis Pneumonia in a Heart Transplant Recipient. TANAFFOS (Respiration), 17(3), 203-206.
MLA
Abolghasemi, S., Sharif-Kashani, B., Naghashzadeh, F., Marjani, M., Monir, A., Doroudinia, A., & Tabarsi, P. "Caspofungin as Salvage Therapy for Pneumocystis Pneumonia in a Heart Transplant Recipient", TANAFFOS (Respiration), 17, 3, 2018, 203-206.
HARVARD
Abolghasemi S., Sharif-Kashani B., Naghashzadeh F., Marjani M., Monir A., Doroudinia A., Tabarsi P. (2018). 'Caspofungin as Salvage Therapy for Pneumocystis Pneumonia in a Heart Transplant Recipient', TANAFFOS (Respiration), 17(3), pp. 203-206.
CHICAGO
S. Abolghasemi, B. Sharif-Kashani, F. Naghashzadeh, M. Marjani, A. Monir, A. Doroudinia & P. Tabarsi, "Caspofungin as Salvage Therapy for Pneumocystis Pneumonia in a Heart Transplant Recipient," TANAFFOS (Respiration), 17 3 (2018): 203-206,
VANCOUVER
Abolghasemi S., Sharif-Kashani B., Naghashzadeh F., Marjani M., Monir A., Doroudinia A., Tabarsi P. Caspofungin as Salvage Therapy for Pneumocystis Pneumonia in a Heart Transplant Recipient. TANAFFOS (Respiration). 2018;17(3):203-206.
