National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran TANAFFOS (Respiration) 1735-0344 1 1(winter) 2002 01 01 Factors Contributing to Pneumothorax in Transthoracic CT-Guided Needle Aspiration Biopsy 15 21 241905 EN Bakhshayesh-Karam M Department of Radiology, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Zahirifard S Department of Radiology, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Mohsen Ghofrani M Department of Radiology, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Fadaizadeh L Department of Radiology, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Journal Article 2021 01 28 Background: We studied pneumothorax as a complication of transthoracic CT-guided needle aspiration biopsy, and its correlation with different variables were determined. Materials & Methods: This cross-sectional study was performed on 145 consecutive patients, aged 9-87 years (mean 55.3+17.6; M/F=1.6), during a 6-month period. We reviewed the pathology results of 150 biopsy specimens obtained from the cases, and assessed the effect of lesion size, depth, patient age and patient emphysema on pneumothorax rate. Results: Lesion size ranged 1-18 cm (mean 6.5+3.4 cm). 95 lesions had zero distance from the chest wall, which were all taken into account in our calculations.Pneumothorax rate was 6 percent, and we found that lesion depth (p <0.05), lesion size (p=0.069), patient age (p=0.058,) and presence of emphysema (p <0.001) are significantly associated with increasing pneumothorax rate (CI=90%). Conclusion: Lesion depth, lesion size, patient age, and emphysema significantly increase the rate of pneumothorax during transthoracic CT-guided needle biopsy.(Tanaffos 2002;1(1):15-21)

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