National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran TANAFFOS (Respiration) 1735-0344 1 4(autumn) 2002 12 01 Electrocardiographic and Echocardiographic Findings in Patients with Pulmonary Sarcoidosis 69 72 241564 EN Babak Sharif-Kashani Cardiology Unit, Neda Behzadnia Cardiology Unit, 0000-0001-8963-4285 Shabnam Shokoufi-Moghiman Cardiology Unit, Hamid Reza Jamaati Department of Pulmonary Medicine, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Mohammad Reza Masjedi Department of Pulmonary Medicine, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Journal Article 2021 01 07 Background: Sarcoidosis is a multisystemic granulomatous disease, in which cardiac involvement is one of the most important causes of death. Conduction abnormalities are the most common cardiac finding. Materials and Methods: Electrocardiographic and echocardiographic changes of 40 patients with pulmonary sarcoidosis who referred to a cardiac unit were evaluated. For all cases, a complete history, 12-lead ECG, and a transthoracic echocardiogram were achieved. None of them had history of underlying heart disease. Data analysis was performed using descriptive statistical parameters. Results: The study population included 24 females and 11 males with the mean (±SD) age of 47.8±8.6 years. Echocardiographic indices including systolic function and total cardiac function indices as well as the size of cavities and valves status were in normal limit in most patients. Only in 5% of patients, ejection fraction (EF) was slightly diminished. In 42.5% of cases, diastolic dysfunction was detected. Electrocardiographic evaluation showed first degree AV block only in one case and T inversion in leads V1-V6 in another subject. Conclusion: Our study showed that cardiac involvement presenting as electrocardiopraphic abnormality was seen in 2 cases. Diastolic involvement was a remarkable finding in our study. This as well as a slight decrease of 5% in EF requires further investigation. A study with a greater sample size, better follow up, and using other diagnostic means, can be helpful. (Tanaffos 2002; 1(4): 69-72) https://www.tanaffosjournal.ir/article_241564_4a69efd7cc4302c5941a1f3c45b1db81.pdf