National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran TANAFFOS (Respiration) 1735-0344 11 3(summer) 2012 10 01 Pulmonary Function and Methacholine Challenge Tests in Patients with Ulcerative Colitis 23 27 241087 EN Maryam Taherzadeh Department of Pulmonology Homayoon Vahedi Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Keivan Gohari Moghadam Department of Pulmonology Javad Shakeri Department of Pulmonology Mehedi Chaharmahali Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Omalbanin Paknejad Department of Pulmonology Journal Article 2020 12 30 Background: Ulcerative colitis is an inflammatory chronic disease which is believed to be a multi organ condition. The prevalence of ulcerative colitis is reportedly increasing in Iran presenting with the same clinical characteristics as in developing countries. Pulmonary manifestations of ulcerative colitis are increasingly reported. In this study, we investigated the incidence of bronchial hyper-responsiveness (BHR) in ulcerative colitis (UC) patients. Materials and Methods: Fifty-one UC patients with definite diagnosis referred to Shariati Hospital, Tehran, Iran, were selected to be evaluated with methacholine challenge test from October 2010 to October 2011. Patients were compared for their methacholine test outcome and its association with age, sex, diagnosis time, and disease activity. Results: The median age was 41 (range 15 to 65) years. The median time of diagnosis was 7 (range https://www.tanaffosjournal.ir/article_241087_27deda03b9f342306786c4bd7af99907.pdf