National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran TANAFFOS (Respiration) 1735-0344 13 4 1999 11 30 Diagnostic Accuracy of Chest Ultrasonography versus Chest Radiography for Identification of Pneumothorax: A Systematic Review and Meta-Analysis 29 40 240894 EN Ali Ebrahimi Trauma Research Center, Baqiyatallah University of Medial Sciences, Tehran, Iran Mahmoud Yousefifard Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Hossein Mohammad Kazemi Trauma Research Center, Baqiyatallah University of Medial Sciences, Tehran, Iran, Hamid Reza Rasouli Trauma Research Center, Baqiyatallah University of Medial Sciences, Tehran, Iran, Hadi Asady Department of Occupational Health Engineering, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali Moghadas Jafar Department of Emergency Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran, Mostafa Hosseini Department of Epidemiology and Biostatistics, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Journal Article 2020 12 27 Background: Early detection of pneumothorax is critically important. Several studies have shown that chest ultrasonography (CUS) is a highly sensitive and specific tool. The present systematic review and meta-analysis was designed to evaluate the diagnostic accuracy of CUS and chest radiography (CXR) for detection of pneumothorax. Materials and Methods: The literature search was conducted using PubMed, EMBASE, Cochrane, CINAHL, SUMSearch, Trip databases, and review article references. Eligible articles were defined as diagnostic studies on patients suspected for pneumothorax who underwent chest computed tomography (CT) scan and those assessing the screening role of CUS and CXR. Results: The analysis showed the pooled sensitivity and specificity of CUS were 0.87 (95% CI: 0.81-0.92; I2= 88.89, p <0.001) and 0.99 (95% CI: 0.98-0.99; I2= 86.46, p <0.001), respectively. The pooled sensitivity and specificity of CXR were 0.46 (95% CI: 0.36-0.56; I2= 85.34, p <0.001) and 1.0 (95% CI: 0.99-1.0; I2= 79.67, p <0.001), respectively. The Meta regression showed that the sensitivity (0.88; 95% CI: 0.82 - 0.94) and specificity (0.99; 95% CI: 0.98 - 1.00) of ultrasound performed by the emergency physician was higher than by non-emergency physician. Non-trauma setting was associated with higher pooled sensitivity (0.90; 95% CI: 0.83 – 0.98) and lower specificity (0.97; 95% CI: 0.95 – 0.99). Conclusion: The present meta-analysis showed that the diagnostic accuracy of CUS was higher than supine CXR for detection of pneumothorax. It seems that CUS is superior to CXR in detection of pneumothorax, even after adjusting for possible sources of heterogeneity. https://www.tanaffosjournal.ir/article_240894_06c1b6af918d033b6e09835ffeda44f4.pdf