National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran TANAFFOS (Respiration) 1735-0344 11 4(autumn) 2012 12 01 Pattern of Pulmonary Function Test Abnormalities in Anthracofibrosis of the Lungs 34 37 240113 EN Majid Mirsadraee Department of Internal Medicine, Islamic Azad University – Mashhad Branch, Mashhad, Iran, Amir Asnaashari Department of Pulmonary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Davood Attaran Department of Pulmonary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Journal Article 2020 12 23 Background: The objective of this study was to discuss the spirometric characteristics of anthracofibrosis which is a from of bronchial anthracosis associated with deformity. Materials and Methods: Forty anthracofibrosis subjects who were diagnosed with bronchoscopy were enrolled in this prospective study. Static and dynamic spirometry plus lung volumes and diffusion capacity were measured in this group and compared to a healthy control group. Results: Dyspnea (95%), cough (86%) and wheezing (68%) were the most frequent clinical findings. Spirometry showed significant decrease in all parameters including VC (FVC), FEV1, FEV1/FVC, FEF25-75 and FEF25-75 /FVC. The low value of FEV1/FVC and FEF25-75 and the increment of RV were in favor of obstructive patterns in 95% of subjects. Improving the obstruction with bronchodilator was not significant and diffusion capacity was mostly normal. Conclusion: Anthracofibrosis should be added to the list of chronic obstructive pulmonary diseases. https://www.tanaffosjournal.ir/article_240113_2177331ff6bed5577ae762679551045a.pdf