%0 Journal Article %T Comparison of Lymphocyte Number and Their Subsets in Patients with Diabetes Mellitus Type II, Tuberculosis and Concomitant TB and Diabetes %J TANAFFOS (Respiration) %I National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran %Z 1735-0344 %A Mansoori, Davood %A Jamaati, Hamid Reza %A Arami, Siamak %A Zadsar, Maryam %A Abbasian, Ladan %A Esteghamati, Ali Reza %A Velayati, Ali Akbar %D 2002 %\ 12/01/2002 %V 1 %N 4(autumn) %P 45-50 %! Comparison of Lymphocyte Number and Their Subsets in Patients with Diabetes Mellitus Type II, Tuberculosis and Concomitant TB and Diabetes %K tuberculosis %K Cellular Immunity %K Diabetes Mellitus %K Lymphocyte %R %X Background: Diabetics are prone to tuberculosis infection in part due to cellular immunity dysfunction, but the precise mechanism has not been fully understood yet. Materials and Methods: This study was performed in NRITLD between August 1999 and August 2001 to elucidate the quantitative status of cellular immunity. We measured the number of B lymphocytes, T lymphocytes, Natural Killer (NK) cells, and their sub-units in three groups of patients with diabetes mellitus (DM), pulmonary tuberculosis (TB) and pulmonary tuberculosis associated with DM (TB+ DM); and compared their results with age - matched healthy controls. Results: The number of these cells had not significant quantitative difference in TB and also DM patients comparing with healthy controls. A significant difference in total number of T lymphocytes and sub- units of helper T cell was observed in patients with concomitant TB and DM. Conclusion: These results indicate that patients with diabetes mellitus type II do not quantitatively develop cellular immunity dysfunction, a finding that may be seen in patients with concomitant TB and DM. (Tanaffos 2002; 1(4): 45-50) %U https://www.tanaffosjournal.ir/article_241561_ea0c17bf585a92ff88ef1fb3aadf12a0.pdf