Acute Respiratory Failure as the First Manifestation of Antisynthetase Syndrome

Authors

1 Department of Respiratory, Research Unit 12SP06, Faculty of Medicine of Tunis, El Manar Tunis University, Rabta hospital, Tunisia.

2 Department of Respiratory, Research Unit 12SP06, Faculty of Medicine of Tunis, El Manar Tunis University, Rabta hospital, Tunisia

Abstract

We report the case of a 40-year-old man with acute respiratory failure syndrome that later proved to be an initial manifestation of antisynthetase syndrome. The diagnosis of this rare combination of a connective tissue disease and an acute respiratory failure is difficult in a previously asymptomatic patient. Early diagnosis and immunosuppressive therapy started precociously prevented the disease progression and resulted in a good outcome.

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