TY - JOUR ID - 242251 TI - Achalasia as a Potential Predisposing Factor for Lung Allograft Rejection JO - TANAFFOS (Respiration) JA - RSPR LA - en SN - 1735-0344 AU - Najafizadeh, Katayoun AU - Ghorbani, Fariba AU - Shiehmorteza, Masoud AU - Mohammadtaheri, Zohreh AU - Jamali, Masoud AU - Mohammadi, Forozan AU - Amiri, Majid Valiollah Pour AU - Abbasi, Azizollah AD - Department of Pulmonary Medicine, AD - Department of Pulmonary Medicine, AD - Department of Clinical Anatomical Pathology, AD - Lung Transplantation Research Center, AD - Department of Infectious Disease, AD - Lung Transplantation Research Center, Y1 - 2008 PY - 2008 VL - 7 IS - 3(summer) SP - 69 EP - 72 KW - Lung transplantation KW - Achalasia KW - Persistant allograft rejection KW - Pulmonary fibrosis DO - N2 - Microaspiration secondary to gastroesophageal reflux has been postulated to be a predisposing factor for development of bronchiolitis obliterans syndrome after lung transplantation. Esophageal manometry and ambulatory pH monitoring have been suggested as a screening test in patients with end-stage lung disease. We report a single lung transplant patient who developed allograft rejection presumed to be due to underlying achalasia as the patient’s clinical status and lung function improved markedly following the treatment of achalasia. The potential cause-effect association between esophageal disorder and allograft rejection and the clinical importance of the screening in this group to improve the survival rate after lung transplantation is proposed. (Tanaffos 2008; 7(3): 69-72) UR - https://www.tanaffosjournal.ir/article_242251.html L1 - https://www.tanaffosjournal.ir/article_242251_216a37dcab1e60e9901682877908b644.pdf ER -