TY - JOUR ID - 241357 TI - Fiberoptic Bronchoscopy: Correlation of Cytology and Biopsy Results JO - TANAFFOS (Respiration) JA - RSPR LA - en SN - 1735-0344 AU - Taheri, Zohreh Mohammad AU - Mohammadi, Forozan AU - Karimi, Shirin AU - Darjani, Hamidreza Jabbar AU - Seyfollahi, Leila AU - Emami, Habib AU - Bahadori, Moslem AU - Masjedi, Mohammad Reza AD - Department of Clinical Anatomical Pathology, AD - Department of Pulmonary Medicine AD - Department of Clinical Anatomical Pathology AD - Tobacco Prevention and Control Research Center, NRITLD, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN Y1 - 2007 PY - 2007 VL - 6 IS - 2(spiring) SP - 46 EP - 50 KW - Fiberoptic bronchoscopy KW - Bronchial biopsy KW - Bronchial washing KW - Cytology KW - Histology KW - Concordance KW - agreement DO - N2 - Background: Fiberoptic bronchoscopy is a diagnostic method for respiratory diseases. At present, its diagnostic yield has been increased by different cytologic and histologic procedures by convention. Objective: This study was conducted to evaluate the concordance and agreement between cytologic and histologic findings in conventional diagnostic bronchoscopic methods (washing and biopsy) for lung malignancies. Materials and Methods: This was a cross-sectional study performed on 2076 cases of bronchial biopsy and bronchial washing between 1996 and 2003. Results: Of 2163 patients who underwent fiberoptic bronchoscopy after omitting 87(4%) cases due to unsatisfactory specimens, 2076 cases were studied including 832 (36.9%) females and 1244 (63.1%) males in the age range of 2 to 100 years, ( mean age 57.7±16.3 yrs). Male to female ratio was 1.5. Malignancy was diagnosed in 657(31.6%) biopsy and 283(13.6%) cytology specimens. Two hundred and sixty-five cases had malignant lesions according to both bronchial biopsy and bronchial washing; therefore, Kappa coefficient in both methods was 46.7% (P value = 0.000). Concordance rate was 77.4%. Ninety-seven point three percent of malignant cases were diagnosed by biopsy and 41.9% by cytology. Cytology contributed to an additional diagnostic rate of 2.6%. Conclusion: Kappa agreement is classified as fair and although there is a very good concordance between the two sampling techniques, the diagnostic yield of cytology for malignancy must be improved by combination of multiple assays. (Tanaffos 2007; 6(2): 46-50) UR - https://www.tanaffosjournal.ir/article_241357.html L1 - https://www.tanaffosjournal.ir/article_241357_b3b4cdf3867cb0b5bca6969944efd766.pdf ER -