TY - JOUR ID - 241148 TI - Cutaneous Anergy in Patients Receiving Long Term Hemodialysis JO - TANAFFOS (Respiration) JA - RSPR LA - en SN - 1735-0344 AU - Aminzadeh, Zohreh AU - Gachkar, Latif AU - Mirsaeidi, Mehdi AU - Darazam, Ilad Alavi AU - Kiani, Arda AU - Valiollahpour, Majid AU - Ghasemi, Shahin AU - Sadeghi, Hosein AU - Alavi, Farhad AU - Moosavi, Mohammad Jafar AU - Akbari, Asghar AU - Mansoori, Davood AU - Shahidi, Mojtaba AU - Jalali, Mehran AU - Pourfarziani, Vahid AU - Kazempour Dizaji, Mehdi AU - Saba, Hossein AD - 1Department of Infectious Diseases, Loghman Hospital, AD - 2Department of Infectious Diseases, NRITLD, AD - Chronic Respiratory Disease Research Center AD - 3Department of Infectious Diseases, Labaffi Nejad Hospital, Shaheed Beheshti University of Medical Sciences and Health Services, TEHRAN-IRAN AD - Tehran University of Medical Sciences AD - Erfan General Hospital, Tehran- Iran. AD - Erfan General Hospital, Tehran- Iran AD - Department of Infectious Diseases, NRITLD, Y1 - 2002 PY - 2002 VL - 1 IS - 2(spring) SP - 21 EP - 26 KW - Cutaneous anergy KW - Hemodialysis KW - Delayed Type Hypersensitivity(DTH) KW - tuberculosis DO - N2 - Background: Hemodialysis patients are at risk of acquiring tuberculosis, which is most often due to reactivation of theinfection. As a result, screening for tuberculosis is recommended in hemodialysis patients. In this study, the rate ofresponse to cutaneous PPD along with tetanus and diphteria toxoid antigens have been evaluated to define in hemodialysis patients.Materials and Methods: This clinical trial was conducted on 67 chronic hemodialysis patients in Labbafi Nejad Hospitalduring March- May 2001. PPD, tetanus and diphtheria toxoid solutions, with 1/10 dilution were administered by Manteauxtechnique and the induration was evaluated 48-72 hours, 7 and 9 days after.Results: Of 64 patients, 18.8% had positive PPD tests and 26.6% had negative anergy tests through the first evaluation.The degree of constancy in the results of PPD and anergy tests during the three-time evaluation period were 23.4% and18.7%, respectively, and the degree of induration was increased or decreased among the rest.Conclusion: Hemodialysis patients are at the increased risk for acquiring tuberculosis. Thus, negative cutaneous PPDresults should certainly be revised and evaluated using anergy tests and repetitive readings of the test results. Attentionmust be paid to the “Delayed Type Hypersensitivity” (DTH) phenomenon presenting for the first time in the analysis ofcutaneous test results. Finally, it is recommended to reconsider the value of cutaneous PPD test and its method ofanalysis in hemodialysis patients. (Tanaffos 2002; 1(2): 21-26) UR - https://www.tanaffosjournal.ir/article_241148.html L1 - https://www.tanaffosjournal.ir/article_241148_889212488fb6bb62a7b50f167bcd8c3d.pdf ER -