ORIGINAL_ARTICLE
Clinicopathologic and Survival Characteristics of Malignant Pleural Mesothelioma Registered in Hospital Cancer Registry
Background: Malignant pleural mesothelioma (MPM) is a rare but fatal thoracic tumor, which in the majority of patients is caused by prolonged exposure to asbestos fibers. We aimed at presenting clinicopathological and treatment outcomes of 60 patients of MPM registered in our hospital cancer registry. Materials and Methods: Demographic characteristics of patients, exposure to asbestos, smoking habit, their clinicopathologic characteristics and survival analysis were described. Results: Sixty patients had MPM. Forty patients (66.7%) were men. The mean age of patients was 55.8±11 years. Chest pain and dyspnea were the most prevalent symptoms (31.7%, and 30%, respectively). Thirty-six (61.7%) patients reported asbestos exposure. The median survival and Progression free survival (PFS) were 10.5 months (0.95CI=9.22-11.78) and 7.57 months (0.95CI=5.68-9.45), respectively. In multivariate analysis, exposure to asbestos and epithelioid subtype significantly extended the survival time. Bilateral involvement, high blood level of LDH and platelet count ≥400,000 significantly shortened the overall survival. Conclusion: MPM is still an important health problem in Iran. Given the aforementioned results, developing a national program to eliminate asbestosrelated diseases according to the world health organization (WHO) recommendation is necessary.
https://www.tanaffosjournal.ir/article_240971_eb694c7838f83c824daccc936cda7a4e.pdf
2014-06-01
6
12
Cancer registry
Malignant pleural mesothelioma
Survival
Kosar
Najmi
1
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,
AUTHOR
Adnan
Khosravi
2
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,
AUTHOR
Sharare
Seifi
3
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,
AUTHOR
Habib
Emami
4
Tobacco Prevention and Control Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
LEAD_AUTHOR
Samira
Chaibakhsh
5
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,
AUTHOR
Golnar
Radmand
6
Department of Epidemiology and Biostatistics, NRITLD, Shahid Beheshti University Of Medical Sciences, Tehran, Iran,
AUTHOR
Kian
Khodadad
7
Department of Internal Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
AUTHOR
ORIGINAL_ARTICLE
Efficacy of Dressing with Absorbent Foam versus Dressing with Gauze in Prevention of Tracheostomy Site Infection
Background: Tracheostomy site infection can cause numerous problems. Absorbent foam dressing may be able to prevent proliferation of infectious microorganisms by absorbing the tracheostomy stoma exudate. This study aimed to compare the efficacy of absorbent foam with gauze dressing for prevention of tracheostomy site infection. Materials and Methods: In this double-blind randomized clinical trial, 80 patients (18 to 60 years) hospitalized in the intensive care unit (ICU) due to severe head injury were randomly divided into two groups and early tracheostomy was done for them during the first 2 days. In the first group, gauze was used as tracheostomy site dressing, while in the second, absorbent foam, was placed. Tracheostomy site was checked daily for any sign of infection and samples were taken from the stoma for culture in case of presence of any sign of infection. Results: Of a total of 80, 11 had tracheostomy site infection (13.75%), including 7 (17.5%) in the gauze group and 4 (10%) in the foam group. The difference in this regard between the two groups was not significant (P=0.051). Also, the dominant strains in the culture of gauze group were hospital-acquired Gramnegative bacteria (particularly Acinetobacter), while in the foam group, Grampositives and more commonly Staphylococcus epidermidis were found. Conclusion: Absorbent foam dressing is not superior to gauze dressings for prevention of tracheostomy site infection.
https://www.tanaffosjournal.ir/article_240972_416e4b1836f565038306783bc346de13.pdf
2014-06-01
13
19
Foam dressing
Infection
Tracheostomy
Mehdi
Ahmadinegad
1
Department of Anesthesiology and Critical Care, Kerman University of Medical Sciences, Kerman, Iran,
AUTHOR
Mohammad Reza
Lashkarizadeh
2
Department of Surgery, Kerman University of Medical Sciences, Kerman, Iran,
AUTHOR
Minoo
Ghahreman
3
Department of Anesthesiology and Critical Care, Kerman University of Medical Sciences, Kerman, Iran,
AUTHOR
Mohammad
Shabani
4
Kerman Neuroscience Research Center, Neuropharmacology Institute, Kerman, Iran,
AUTHOR
Mahsa
Mokhtare
5
Department of Anesthesiology and Critical Care, Kerman University of Medical Sciences, Kerman, Iran,
AUTHOR
Maryam
Ahmadipour
6
Kerman University of Medical Sciences, Kerman, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Lean Body Mass Can Predict Lung Function in Underweight and Normal Weight Sedentary Female Young Adults
Background: A previous cross-sectional study found reduced lung function among over weight and obese students in Zanjan city. However, there is no reliable evidence about the respiratory function of underweight and normal weight students. The objective of this study was to evaluate lung function and develop prediction equations in underweight and normal weight female young adults residing in Soltanieh city near Zanjan. Materials and Methods: A cross sectional study was conducted on underweight (n=29, mean age=16±0.84 years) and normal weight (n=38, mean age=15.9±0.86 years) sedentary female young adults. Fat mass (FM) was measured by Omron Body Fat Monitor FB-3002. Lean body mass (LBM), waist to hip ratio (WHR), body mass index (BMI) and waist circumference (WC) were calculated. Maximum oxygen uptake was calculated using Queen’s College step test. Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were recorded, using Spirolab III spirometer. Independent t test, Pearson’s correlation test and stepwise linear regression analysis were used for data analysis. Results: FVC and FEV1 were significantly lower than the reference values in both groups (p <0.05). LBM was significantly correlated with FVC and FEV1 in underweight and normal weight groups (p <0.05). Regression equations were derived to predict FVC and FEV1 using LBM. Conclusion: This study suggests that dynamic lung functions are poor in underweight and normal weight sedentary female young adults residing in Soltanieh city and LBM plays a significant role in their lung function.
https://www.tanaffosjournal.ir/article_240974_80f9919c3cbf83c6a77db7a5346d128a.pdf
2014-06-01
20
26
Underweight
Normal weight
Lung Function
Ahmad
Azad
1
Department of Physical Education and Exercise Science, Faculty of Humanities, University of Zanjan, Zanjan, Iran
LEAD_AUTHOR
Akram
Zamani
2
Department of Physical Education, Soltanieh Education Organization, Soltanieh, Zanjan, Iran
AUTHOR
ORIGINAL_ARTICLE
Spirometry Values for Detecting a Restrictive Pattern in Occupational Health Settings
Background: Pulmonary function tests are valuable measures for diagnosis and management of respiratory diseases. In the field of occupational medicine, spirometry is commonly performed, and in a considerable number of spirometries during occupational health evaluations, restrictive pattern is observed without any respiratory symptoms and may necessitate referral of the subject for body plethysmography, which is an expensive test. In this study, we evaluated the diagnostic accuracy of spirometry for detection of restrictive lung pattern in an occupational setting. Materials and Methods: In a cross-sectional study from 2008 to 2012, 1224 subjects were selected and entered in the study out of 1,486 individuals referred for annual spirometry. Selected subjects underwent spirometry and body plethysmography. Subjects were divided into two groups of restrictive and non-restrictive patterns and then sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of spirometry for detection of restrictive lung pattern were calculated using total lung capacity measured by plethysmography as the gold standard. Receiver operating characteristic (ROC) curves were used as well. Results: Spirometry showed sensitivity, specificity, PPV and NPV of 97.75%, 73.04%, 73.72% and 97.67% for FVC< lower limit of normal (LLN) and 98.68%, 78.00%, 77.31% and 98.83% for FVC< LLN along with FEV1/FVC≥ LLN, respectively. According to the ROC curve, the best cut-off point for FVC for detection of restrictive lung pattern was 70%. Conclusion: This study showed that spirometry is a useful method in occupational health evaluations to rule out restrictive lung patterns with acceptable accuracy; however, it is not an accurate tool for detection of restrictive lung pattern in an occupational setting. Simultaneous use of FVC and FEV1/FVC for detection of restriction increases the predictive value of spirometry.
https://www.tanaffosjournal.ir/article_240975_d9d518538763cf9d12519949b312634e.pdf
2014-06-01
27
34
Spirometry
Body plethysmography
Restrictive lung pattern
Occupational health evaluation
Amir Houshang
Mehrparvar
1
Occupational Medicine Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences,
AUTHOR
Mohammad Javad
Zare Sakhvidi
2
Occupational Health Department, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
AUTHOR
Mehrdad
Mostaghaci
3
Occupational Medicine Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences
LEAD_AUTHOR
Mohmmad Hossein
Davari
4
Occupational Medicine Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences
AUTHOR
Seyed Hesam
Hashemi
5
Occupational Medicine Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences,
AUTHOR
Zohreh
Zare
6
Occupational Medicine Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences,
AUTHOR
ORIGINAL_ARTICLE
Relationship of Occupational and Non-Occupational Stress with Smoking in Automotive Industry Workers
Background: Tobacco use is the second cause of death and first cause of preventable mortality worldwide. Smoking in the workplace is particularly concerning. Smoking-free workplaces decrease the risk of exposure of nonsmoking personnel to cigarette smoke. Recent studies have mostly focused on the effect of daily or non-occupational stressors (in comparison with occupational stress) on prevalence of smoking. Occupational stress is often evaluated in workplaces for smoking cessation or control programs, but the role of non-occupational stressors is often disregarded in this respect. Materials and Methods: This cross-sectional study was conducted in an automobile manufacturing company. The response of automotive industry workers to parts of the validated, reliable, Farsi version of Musculoskeletal Intervention Center (MUSIC)-Norrtalje questionnaire was evaluated. A total of 3,536 factory workers participated in this study. Data were analyzed using SPSS and p
https://www.tanaffosjournal.ir/article_240976_cb5abc6312bfde63e7573cb5bd23cbbd.pdf
2014-06-01
35
42
cigarette
Workplace
Occupational stress
Nonoccupational stress
Somayeh
Hassani
1
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Taraneh
Yazdanparast
2
Pediatric Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences,
AUTHOR
Seyed Mohammad
Seyedmehdi
3
Telemedicine Research Center, NRITLD, Shahid Beheshti University of Medical Sciences,
LEAD_AUTHOR
Mostafa
Ghaffar
4
Occupational Medicine Department, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Mirsaeed
Attarchi
5
Occupational Medicine Department, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Baharak
Bahadori
6
Occupational Medicine Department, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
ORIGINAL_ARTICLE
Sleep-Disordered Breathing as Presenting Manifestation of Chiari Type I Malformation: A Case Report
Chiari Type I malformation (CM-I) is a rare disorder with displaced cerebellar tonsils through foramen magnum. Here we present a 30-year-old man with severe central and obstructive sleep apneas as presenting manifestations of CM-I. The patient underwent neurosurgery and the follow-up polysomnography revealed the resolution of central apnea while obstructive apnea remained unchanged. Central sleep apnea (CSA) could be associated with an underlying pathology; thus, further investigation is recommended in affected subjects.
https://www.tanaffosjournal.ir/article_240977_e4dfaa6d6f2fa9c0d077d8db09c43934.pdf
2014-06-01
43
46
Chiari type I malformation
Sleep disordered breathing
Central sleep apnea
Parisa
Adimi
1
Chronic Respiratory Diseases Research Center, Department of Pulmonary and Sleep Medicine, National Research Institute of Tuberculosis and Lung diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
AUTHOR
Mehrdad
BakhshayeshKaram
2
Pediatric Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran
AUTHOR
Nazanin
Kiapour
3
Pediatric Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran
AUTHOR
Moein
Foroughi
4
Chronic Respiratory Diseases Research Center, Department of Pulmonary and Sleep Medicine, National Research Institute of Tuberculosis and Lung diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,
LEAD_AUTHOR
ORIGINAL_ARTICLE
Primary Composite Lymphoma of the Lung: a Case Report
Herein, we report a rare case of primary lung lymphoma in a 61 year-old woman with a history of 6-month nonspecific symptoms like dry cough, fever, chills and weight loss. She was admitted to a hospital and received broadspectrum antibiotics but discharged without full recovery. In her second hospital admission, a bronchoscopic evaluation and transbronchial biopsy were performed, which were not diagnostic. Finally, an open lung biopsy was done. Immunohistochemical (IHC) staining of the specimen suggested pulmonary Hodgkin lymphoma. Because of disease recurrence, a second bronchoscopy was performed and endobronchial biopsy revealed transformation to anaplastic lymphoma. In the second recurrence, we decided to reevaluate the last biopsy specimens in greater details. Finally, after conduction of several staining patterns, the diagnosis of primary composite lymphoma of the lung was made.
https://www.tanaffosjournal.ir/article_240978_bd486763749d08ee7f7131ef2bcad304.pdf
1999-11-30
47
49
Pulmonary Hodgkin lymphoma
Anaplastic Lymphoma
Primary lung composite lymphoma
Mohammadali
Saba
1
Department of Internal Medicine, Kashan University of Medical Sciences,
LEAD_AUTHOR
Majeed
Ehsani
2
Department of Internal Medicine, Kashan University of Medical Sciences,
AUTHOR
Mehdi
Moosavian
3
Department of Internal Medicine, Kashan University of Medical Sciences,
AUTHOR
Alireza
Khooeei
4
Mashhad University of Medical Sciences
AUTHOR
ORIGINAL_ARTICLE
Supraglottic Hemangioma as a Rare Cause of Recurrent Hemoptysis: A New Treatment Modality with Argon Plasma Coagulation (APC)
Adult laryngeal hemangiomas are rare and mainly involve the supraglottic region. Most common symptoms include dysphagia, dysphonia, shortness of breath and occasionally recurrent bleeding which sometimes cause a diagnostic dilemma for pulmonologists and head and neck surgeons. There is no consensus about the most appropriate treatment modality for laryngeal hemangiomas. We present a case of supraglottic hemangioma in an adult female, which was diagnosed by fiberoptic bronchoscopy and coagulated by Argon plasma coagulation (APC) with no complication.
https://www.tanaffosjournal.ir/article_240979_70ce079258205a8fc94d47baabdd76a2.pdf
2014-06-01
50
52
Hemangioma
Bronchoscopy
Argon plasma coagulation
Akbar
Sharifi
1
Tuberculosis and Lung Disease Research Center. Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
Masoud
Nazemieh
2
Tuberculosis and Lung Disease Research Center. Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
Majid
Moghadaszadeh
3
Department of Internal Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
LEAD_AUTHOR