@article { author = {Alaei, Kamyar and Mansoori, Davood and Alaei, Arash}, title = {The Effect of One Year INH Prophylaxis in Reduction of Clinical TB in HIV-Infected Injecting Drug User Males}, journal = {TANAFFOS (Respiration)}, volume = {2}, number = {1(winter)}, pages = {57-61}, year = {2003}, publisher = {National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran}, issn = {1735-0344}, eissn = {2345-3729}, doi = {}, abstract = {Background: Due to increased prevalence of tuberculosis among HIV-infected patients, INH (Isoniazid) chemoprophylaxis has a major impact on the development of clinical tuberculosis. Materials and Methods: For the evaluation of INH effect on prevention, we used INH, 300 mg daily for 115 available TST (tuberculin skin test) positive HIV-infected patients for twelve months. Results: During three-year follow up, only twelve patients developed tuberculosis which was significantly lower than minimum estimated rate among these patients (>10% per year). Conclusion: We conclude that INH prophylaxis was effective method to prevent clinical tuberculosis among TST positive HIV-infected patients. (Tanaffos 2003; 2(5): 57-61)}, keywords = {tuberculosis,HIV infection,Isoniazid,Prophylaxis}, url = {https://www.tanaffosjournal.ir/article_241556.html}, eprint = {https://www.tanaffosjournal.ir/article_241556_54006ee8647b52169a355ef438fedca1.pdf} }