@article { author = {Aminzadeh, Zohreh and Gachkar, Latif and Mirsaeidi, Mehdi and Darazam, Ilad Alavi and Kiani, Arda and Valiollahpour, Majid and Ghasemi, Shahin and Sadeghi, Hosein and Alavi, Farhad and Moosavi, Mohammad Jafar and Akbari, Asghar and Mansoori, Davood and Shahidi, Mojtaba and Jalali, Mehran and Pourfarziani, Vahid and Kazempour Dizaji, Mehdi and Saba, Hossein}, title = {Cutaneous Anergy in Patients Receiving Long Term Hemodialysis}, journal = {TANAFFOS (Respiration)}, volume = {1}, number = {2(spring)}, pages = {21-26}, year = {2002}, publisher = {National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran}, issn = {1735-0344}, eissn = {2345-3729}, doi = {}, abstract = {Background: Hemodialysis patients are at risk of acquiring tuberculosis, which is most often due to reactivation of theinfection. As a result, screening for tuberculosis is recommended in hemodialysis patients. In this study, the rate ofresponse to cutaneous PPD along with tetanus and diphteria toxoid antigens have been evaluated to define in hemodialysis patients.Materials and Methods: This clinical trial was conducted on 67 chronic hemodialysis patients in Labbafi Nejad Hospitalduring March- May 2001. PPD, tetanus and diphtheria toxoid solutions, with 1/10 dilution were administered by Manteauxtechnique and the induration was evaluated 48-72 hours, 7 and 9 days after.Results: Of 64 patients, 18.8% had positive PPD tests and 26.6% had negative anergy tests through the first evaluation.The degree of constancy in the results of PPD and anergy tests during the three-time evaluation period were 23.4% and18.7%, respectively, and the degree of induration was increased or decreased among the rest.Conclusion: Hemodialysis patients are at the increased risk for acquiring tuberculosis. Thus, negative cutaneous PPDresults should certainly be revised and evaluated using anergy tests and repetitive readings of the test results. Attentionmust be paid to the “Delayed Type Hypersensitivity” (DTH) phenomenon presenting for the first time in the analysis ofcutaneous test results. Finally, it is recommended to reconsider the value of cutaneous PPD test and its method ofanalysis in hemodialysis patients. (Tanaffos 2002; 1(2): 21-26)}, keywords = {Cutaneous anergy,Hemodialysis,Delayed Type Hypersensitivity(DTH),tuberculosis}, url = {https://www.tanaffosjournal.ir/article_241148.html}, eprint = {https://www.tanaffosjournal.ir/article_241148_889212488fb6bb62a7b50f167bcd8c3d.pdf} }