@article { author = {Abolghasemi, Sara and Sharif-Kashani, Babak and Naghashzadeh, Farah and Marjani, Majid and Monir, Afshin and Doroudinia, Atousa and Tabarsi, Payam}, title = {Caspofungin as Salvage Therapy for Pneumocystis Pneumonia in a Heart Transplant Recipient}, journal = {TANAFFOS (Respiration)}, volume = {17}, number = {3}, pages = {203-206}, year = {2018}, publisher = {National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran}, issn = {1735-0344}, eissn = {2345-3729}, doi = {}, abstract = {Pneumocystis pneumonia (PCP) is a common opportunistic infection in immunocompromised patients. In general, clinical response to therapy with cotrimoxazole is excellent. However, therapy may be limited by side effects or treatment failure. We present a case of PCP in a 35-year-old male patient with history of heart transplantation and renal failure who was admitted with a 10- day history of fever, nonproductive cough and elevated level of creatinine with a diagnosis of PCP confirmed by chest radiography and in bronchoalveolar lavage specimens. He was treated with trimethoprim-sulphamethoxazole (SMZ/TMP) and primaquine but treatment was completed with reduced dosage of cotrimoxazole, primaquine and with the addition of caspofungin. This therapy was effective and without any adverse effects in a patient with elevated level of creatinine}, keywords = {Pneumocystis Pneumonia,chronic renal failure,Caspofungin}, url = {https://www.tanaffosjournal.ir/article_240058.html}, eprint = {https://www.tanaffosjournal.ir/article_240058_20c1945abd5a11051ea9109ec9a2dd36.pdf} }